产品货号 :  mlR16777

英文名称 :  KLRA1

中文名称 :  KLRA1蛋白抗体

别    名 :  Killer cell lectin like receptor subfamily A, member 1; LY 49L; KLRA1_MOUSE; Ly49; Ly-49; LY49L.  

研究领域 :  免疫学  细胞膜受体  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Mouse,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  60kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from mouse KLRA1:31-130/262 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

Note: This locus was originally considered to be protein coding, but has been reclassified as a transcribed pseudogene because all associated transcripts are candidates for nonsense-mediated decay (NMD). PMID: 10369937 and 16492762 also state that this locus is likely to be a pseudogene. [14 Jul 2009]

Function:

Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.

Subunit:

Homodimer; disulfide-linked.

Subcellular Location:

Membrane; Single-pass type II membrane protein.

Tissue Specificity:

High, in T-lymphoma lines, very low in normal lymphocytes.

Similarity:

Contains 1 C-type lectin domain.

SWISS:

Q925C6

Gene ID:

16627

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.