产品货号 :  mlR20064

英文名称 :  GRTP1

中文名称 :  生长激素调节TBC蛋白1抗体

别    名 :  FLJ22474; Growth hormone-regulated TBC protein 1; Grtp1; GRTP1_HUMAN; MGC138328; MGC138330; OTTHUMP00000018752; TBC1 domain family member 6; TBC1 domain family, member 6; TBC1D6.  

研究领域 :  细胞生物  信号转导  生长因子和激素  G蛋白偶联受体  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  39kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human GRTP1:231-336/336

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   GRTP1 is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events.

Function:

May act as a GTPase-activating protein for Rab family protein(s).

Similarity:

Contains 1 Rab-GAP TBC domain.

SWISS:

Q5TC63

Gene ID:

79774

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.