产品货号 :  mlR17004

英文名称 :  KIAA1430

中文名称 :  KIAA1430蛋白抗体

别    名 :  DKFZp434F1728; FLJ21225; Hypothetical protein LOC57587; K1430_HUMAN; Kiaa1430; UPF0501 protein KIAA1430.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Cow, Horse, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  59kDa

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human KIAA1430:321-420/532

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  KIAA1430 is a 532 amino acid protein that is a member of the UPF0501 family and contains a single coiled coil domain. KIAA1430 is post-translationally phosphorylated at threonine 133 as well as serine 138 and 139. Alternatively spliced into two isoforms, the gene encoding KIAA1430 maps to human chromosome 4. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Similarity:

Belongs to the UPF0501 family.

SWISS:

Q9P2B7

Gene ID:

57587

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.