产品货号 : mlR16994
英文名称 : KIAA1191
中文名称 : KIAA1191蛋白抗体
别 名 : IR2155535; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; P33MX_HUMAN; Transmembrane protein 2 like; Putative monooxygenase p33MONOX; Brain-derived rescue factor p60MONOX; Flavin monooxygenase motif-containing protein of 33 kDa.
研究领域 : 肿瘤 细胞生物 免疫学 神经生物学 肿瘤细胞生物标志物
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 33kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human KIAA1191:51-150/305
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 KIAA1199 belongs to the TMEM2 family and contains 4 PbH1 repeats. It is expressed in the inner ear. It is expressed in cochlea and vestibule tissues and it may be involved in hearing. Defects in KIAA1199 may be a cause of non-syndromic hearing loss. It is also thought that KIAA1199 is a tumor suppressor that may be involved in establishing cellular mortality in normal human cells.
Function:
Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.
Subunit:
Interacts with COBRA1, NOL12 and PRNP.
Tissue Specificity:
Down-regulated in the occipital lobe of an early stage Alzheimer disease patients.
Similarity:
Belongs to the P33MONOX family.
SWISS:
Q96A73
Gene ID:
57179
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
