产品货号 : mlR17652
英文名称 : SPEM1
中文名称 : 精子细胞成熟蛋白1抗体
别 名 : C17orf83; Spem1; SPEM1_HUMAN; Spermatid maturation 1; Spermatid maturation protein 1.
研究领域 : 细胞生物 发育生物学 跨膜蛋白
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 35kDa
细胞定位 : 细胞浆 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human SPEM1:201-300/309
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : SPEM1 is a 309 amino acid transmembrane and cytoplasmic protein that is required for proper cytoplasm removal during spermatogenesis. SPEM1 interacts with both Ran BP-17 and PLIC-1. Since PLIC-1 functions through binding and directing poly-ubiquitinated proteins to the proteasome for degradation, interactions between PLIC-1 and SPEM1 suggest a role in the regulation of protein ubiquitination during spermiogenesis. The SPEM1 gene maps to human chromosome 17p13.1. Comprising over 2.5% of the human genome, chromosome 17 consists of about 81 million bases, encodes over 1,200 genes and has the highest gene density in the genome. Chromosome 17 is also enriched in segmental duplications, ranking third in density among the autosomes.
Function:
Required for proper cytoplasm removal during spermatogenesis.
Subcellular Location:
Membrane. Cytoplasm.
SWISS:
Q8N4L4
Gene ID:
374768
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
