产品货号 :  mlR19436

英文名称 :  PRSS16

中文名称 :  丝氨酸蛋白酶16抗体

别    名 :  FLJ36271; FLJ40714; FLJ44172; Protease serine 16 (thymus); Protease serine 16; Prss16; Serine protease 16; Thymus specific serine peptidase; Thymus-specific serine protease; TSSP; TSSP_HUMAN.  

研究领域 :  细胞生物  信号转导  泛素  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  52kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PRSS16:311-411/514

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

Function:

Protease that may play a role in T-cell development.

Subcellular Location:

Cytoplasmic vesicle. Vesicular, either lysosomal or endosomal.

Tissue Specificity:

Expressed predominantly in cortical thymic epithelial cells.

Similarity:

Belongs to the peptidase S28 family.

SWISS:

Q9NQE7

Gene ID:

10279

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.