产品货号 : mlR16663
英文名称 : INO80D
中文名称 : INO80D蛋白抗体
别 名 : FLJ20309; IN80D_HUMAN; INO80 complex subunit D; OTTHUMP00000206351.
研究领域 : 细胞生物 转录调节因子 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 98kDa
细胞定位 : 细胞核
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human INO80D:331-430/879
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍background:
The INO80 complex contributes to a wide variety of chromatin-dependent nuclear transactions, including transcription, DNA repair and DNA replication. Evolutionarily conserved from yeast to human, theINO80 complex belongs to a subfamily of the ATP-dependent chromatin remodelers and is characterized by a split ATPase domain in the core ATPase subunit. ATP-dependent chromatin remodeling complexes contain ATPases of the Swi/Snf superfamily and alter DNA accessibility of chromatin in an ATP-dependent manner. INO80D (INO80 complex subunit D), is an 878 amino acid protein that is a component of the chromatin-remodeling INO80 complex.
Function:
This protein is a component of the chromatin-remodeling INO80 complex, which is at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.
Subunit:
Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80. {ECO:0000269|PubMed:16230350, ECO:0000269|PubMed:18922472, ECO:0000269|PubMed:21303910}.
Similarity:
Belongs to the INO80D family. {ECO:0000305}.
SWISS:
Q53TQ3
Gene ID:
54891
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
