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您当前的位置:首页 > 抗体 > 锚蛋白重复结构域蛋白50抗体

锚蛋白重复结构域蛋白50抗体

  • 产品货号:mlR9751-1 收藏此商品
  • 销售价:1580.00-2480.00
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产品 :  mlR9751

英文名称 :  ANKRD50

中文名称 :  锚蛋白重复结构域蛋白50抗体

   :  ANKRD50; Ankyrin repeat domain 50; Ankyrin repeat domain-containing protein 50; ANR50_HUMAN; KIAA1223.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

 :  156kDa

细胞定位 :  细胞浆

    :  Lyophilized or Liquid

    :  1mg/ml

 :  KLH conjugated synthetic peptide derived from human ANKRD50:201-300/1429

    :  IgG

纯化方法 :  affinity purified by Protein A

 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background :  

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD50 (ankyrin repeat domain 50) is a 1,429 amino acid phosphoprotein that contains nineteen ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and mosquito, ANKRD50 is encoded by a gene that maps to human chromosome 4q28.1. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which encodes an expanded glutamine tract in cases of Huntington's disease, is located on chromosome 4. FGFR-3 is also encoded by a gene that maps to human chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also linked to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Similarity:

Contains 19 ANK repeats.

SWISS:

Q9ULJ7

Gene ID:

57182

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

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