产品货号 :  mlR7918

英文名称 :  PLK5

中文名称 :  丝氨酸/苏氨酸蛋白激酶5抗体

别    名 :  PLK5; PLK 5; PLK-5; polo like kinase 5, pseudogene; SgK384ps; PLK5_HUMAN.  

研究领域 :  细胞生物  信号转导  细胞周期蛋白  激酶和磷酸酶  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  36kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PLK5:191-280/336

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.

Function:

Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.

Subcellular Location:

Nucleus, nucleolus (By similarity). Cytoplasm.

Tissue Specificity:

Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level).

Similarity:

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

Contains 1 POLO box domain.

Contains 1 protein kinase domain.

SWISS:

Q496M5

Gene ID:

126520

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.