产品货号 :  mlR12831

英文名称 :  STK23

中文名称 :  丝氨酸/苏氨酸蛋白激酶23抗体

别    名 :  Serine/threonine protein kinase 22C; Serine/threonine-protein kinase 22C; Spermiogenesis associated 3; SPOGA3; STK22D; Testis specific kinase 3; Testis specific serine kinase 3; Testis specific serine/threonine kinase 22C; Testis specific serine/threonine protein kinase 3; Testis-specific kinase 3; Testis-specific serine/threonine-protein kinase 3; TSK 3; TSK-3; TSK3; TSSK-3; TSSK3; TSSK3_HUMAN.  

研究领域 :  细胞生物  发育生物学  信号转导  激酶和磷酸酶  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  62kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human STK23:351-450/567

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Function:

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.

Tissue Specificity:

Exclusively expressed in skeletal and heart muscle.

Similarity:

Belongs to the protein kinase superfamily.

CMGC Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

SWISS:

Q9UPE1

Gene ID:

26576

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.