产品货号 :  mlR9314

英文名称 :  MAP7D1

中文名称 :  精氨酸/脯氨酸富含卷曲蛋白1抗体

别    名 :  Arginine/proline rich coiled coil 1; Arginine/proline rich coiled coil domain containing protein 1; Arginine/proline-rich coiled-coil domain-containing protein 1; MA7D1_HUMAN; MAP7 domain containing 1; MAP7 domain containing protein 1; MAP7 domain-containing protein 1; MAP7D1; MGC117315; PARCC1; Proline arginine rich coiled coil 1; Proline/arginine rich coiled coil domain containing protein 1; Proline/arginine-rich coiled-coil domain-containing protein 1; RPRC1.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  93kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MAP7D1/RPRC1:101-200/841

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Subcellular Location:

Cytoplasm, cytoskeleton, spindle.

Similarity:

Belongs to the MAP7 family.

SWISS:

Q3KQU3

Gene ID:

55700

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.