产品货号 :  mlR19602

英文名称 :  SDCCAG3

中文名称 :  结肠癌抗原3抗体

别    名 :  Antigen NY CO 3; NY CO 3; NY-CO-3; SDCG3_HUMAN; OTTHUMP00000022582; SDCCAG 3; Serologically defined colon cancer antigen 3.  

研究领域 :  肿瘤  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  48kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SDCCAG3:221-320/435

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  SDCCAG3 may be involved in modulation of TNF response. It may be involved in presentation of TNFRSF1A on the cell surface.

Function:

May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface (By similarity). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 (PubMed:25278552). Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 (PubMed:23108400).

Subunit:

Interacts with PTPN13, GIT1, VPS35 (PubMed:23108400, PubMed:25278552).

Subcellular Location:

Cytoplasmic

Similarity:

Belongs to the SDCCAG3 family.

SWISS:

Q96C92

Gene ID:

10807

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.