产品货号 : mlR7668
英文名称 : GPR65
中文名称 : G蛋白偶联受体65抗体
别 名 : GPCR GPR65; Dig1; G protein-coupled receptor 65; Gpcr25; GPR65; hTDAG8; Psychosine receptor; T cell death associated gene 8 protein; T-cell death-associated gene 8; TDAG8.
研究领域 : 细胞生物 信号转导 细胞凋亡 细胞周期蛋白 G蛋白偶联受体 G蛋白信号
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 37kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human GPR65:51-120/337 <Extracellular>
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : GPR65 is a member of the G protein coupled receptor family. It has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. The ligand for this protein is psychosine. GPR65 may have a role in activation-induced cell death or differentiation of T cells.
Function:
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation-induced cell death or differentiation of T-cells.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
Q8IYL9
Gene ID:
8477
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
