产品货号 :  mlR0866

英文名称 :  HHV4/CMV

中文名称 :  人类巨细胞病毒抗体

别    名 :  EB2_EBVB9; mRNA export factor EB2; Mta; ORF57 protein homolog; Protein SM; BSLF2; BMLF1; ORF57; HHV4tp2_gp21HHV4; EBV; Human herpesvirus 4 type 2.  

研究领域 :  免疫学  细菌及病毒  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   HHV42

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  53kDa

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from HHV4 2:201-300/479

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   ORF57 herpesvirus core gene UL54 family.

No data available.

Function:

Promotes the nuclear export of a subset of early and late viral mRNAs by interacting with mRNAs and cellular export proteins. Additionally may prevent the establishment of cellular antiviral state, by acting as an alternative splicing factor for cellular RNAs such as STAT1, resulting in a STAT1 mRNA incapable of producing the STAT1alpha isoform.

Subunit:

Interacts with host XPO1 and with the XPO1 export pathway components small GTPase RAN and nucleoporin NUP214. Interacts with host SPEN, OTT1 and OTT3.

Subcellular Location:

Host nucleus. Host cytoplasm. Note=shuttles between the nucleus and the cytoplasm.

Post-translational modifications:

Phosphorylated by cellular protein kinase CK2.

Similarity:

Belongs to the HHV-1 ICP27 protein family.

SWISS:

Q04360

Gene ID:

N/A

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.