产品货号 :  mlR3699

英文名称 :  GPR15

中文名称 :  G蛋白偶联受体15抗体

别    名 :  GPCR GPR15; BOB; G protein coupled receptor 15; G protein coupled receptor GPR15; GPR15_HUMAN; G-protein coupled receptor 15; Brother of Bonzo.  

研究领域 :  肿瘤  细胞生物  免疫学  信号转导  G蛋白偶联受体  细胞表面分子  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Horse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:200-800 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  40kDa

细胞定位 :  细胞浆 细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human GPR15:51-150/360 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

Function:

Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.

Subcellular Location:

Cell membrane; Multi-pass membrane protein.

Similarity:

Belongs to the G-protein coupled receptor 1 family.

SWISS:

P49685

Gene ID:

2838

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

G蛋白偶联受体是一种细胞表面受体，能将细胞外的分子信号传递至细胞内激起细胞反应，对多种细胞行起调控作用。G蛋白偶联受体（GPCR）参与了机体内多种生理过程的调节，是目前治疗多种人类疾病包括代谢性疾病的药物靶点。

产品图片