产品货号 : mlR18155
英文名称 : RELT/TNFRSF19L
中文名称 : 肿瘤坏死因子受体超家族成员19L抗体
别 名 : Receptor expressed in lymphoid tissues; RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L.
研究领域 : 细胞生物 免疫学 神经生物学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 43kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human RELT/TNFRSF19L:101-200/430 <Extracellular>
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Function:
TNFRSF19L may be involved in T cell activation by mediation of the NF kappa B pathway.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cytoplasm
Similarity:
Belongs to the RELT family.
Contains 1 TNFR-Cys repeat
SWISS:
Q969Z4
Gene ID:
84957
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.