产品货号 : mlR4983
英文名称 : TRIP
中文名称 : 肿瘤坏死因子受体相互作用蛋白抗体
别 名 : RING finger protein 206; RNF206; TRAF Interacting Protein; TRAIP; TRIP.
研究领域 : 肿瘤 转录调节因子 细胞膜受体
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Pig, Horse,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 53kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human TRIP:201-300/469
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Function:
Inhibits activation of NF-kappa-B mediated by TNF.
Subunit:
Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex. Interacts with CYLD
Subcellular Location:
Cytoplasm. Cytoplasm, perinuclear region.
Similarity:
Contains 1 RING-type zinc finger.
SWISS:
Q9BWF2
Gene ID:
10293
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
