产品货号 :  mlR19174

英文名称 :  MYO5C

中文名称 :  肌球蛋白5C抗体

别    名 :  Myosin Vc; MYO5C; MYO5C_HUMAN; Unconventional myosin-Vc.  

研究领域 :  细胞生物  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  203,48kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MYO5C:851-950/1742

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Myosin Vc is a 1,742 amino acid protein that is chiefly expressed in non-neuronal tissues. Abundantly expressed in epithelial and glandular tissues including pancreas, prostate, mammary, stomach, colon and lung, Myosin Vc may be involved in transferrin trafficking and is likely to power actin-based membrane trafficking in many physiologically crucial tissues. Myosin Vc is also thought to participate in apical exocytosis of secretory vesicles. Containing one dilute domain, six IQ domains and a myosin head-like domain, Myosin Vc associates with Rab 8.

Function:

May be involved in transferrin trafficking. Likely to power actin-based membrane trafficking in many physiologically crucial tissues.

Tissue Specificity:

Expressed chiefly in non-neuronal tissues. Particularly abundant in epithelial and glandular tissues including pancreas, prostate, mammary, stomach, colon and lung.

Similarity:

Contains 1 dilute domain.

Contains 5 IQ domains.

Contains 1 myosin head-like domain.

SWISS:

Q9NQX4

Gene ID:

55930

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.