产品货号 :  mlR0912

英文名称 :  Batroxobin

中文名称 :  蛇毒巴曲酶/类凝血酶抗体

别    名 :  Agkistrodon halys Batroxobin; Thrombin-like enzyme batroxobin; BX; SVTLE; Bothrops atrox serine proteinase; Defibrase; Fibrinogen-clotting enzyme; Reptilase; Snake venom serine protease; SVSP; Venombin A.  

研究领域 :  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Bothrops atrox

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  25kDa

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from Agkistrodon halys Batroxobin:165-231/255

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   No data available.

Function:

Thrombin-like snake venom serine protease. Cleaves Arg-Gly bonds in fibrinogen alpha chains (FGA).

Subunit:

Secreted.

Subcellular Location:

Expressed by the venom gland.

Similarity:

Belongs to the peptidase S1 family. Snake venom subfamily.

Contains 1 peptidase S1 domain.

SWISS:

N/A

Gene ID:

N/A

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Batroxobin蛇毒巴曲酶蛋白是经生物工程提纯、精制而得丝氨酸蛋白酶。

其作用机制为：

①具有分解血纤维蛋白原、抑制血栓形成作用。 ②具有诱发TPA的释放、增强TPA的作用、促进纤维蛋白溶酶的生成、减少α2-P1和PAI、溶解血栓的作用。

③具有降低血粘度、抑制红细胞凝集、沉降、增强红细胞的血管通过性及变形能力、降低血管阻力以及改善微循环等作用。使溶栓作用快速，缺血部位功能恢复，从而达到治疗和防止复发的效果。