产品货号 : mlR0072
英文名称 : Neurotensin
中文名称 : 神经降压素抗体
别 名 : Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN;
研究领域 : 神经生物学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 1.7/19kDa
细胞定位 : 细胞浆 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide (QLYENKPRRPYIL-C):
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
Function:
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.
Similarity:
Belongs to the neurotensin family.
SWISS:
P30990
Gene ID:
4922
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经降压素 Neurotensin, NT 是一种具有生物活性的单链多肽,后来发现NT也存在于人及其它哺乳动物的胃肠道和其它组织中,如肾上腺髓质、甲状腺等。作为一种脑肠肽,具有神经递质、神经调质和局部激素作用。