产品货号 :  mlR30059

英文名称 :  human CD2-FITC

中文名称 :  FITC标记小鼠抗人CD2单克隆抗体

别    名 :  T-cell surface antigen CD2; CD 2; CD2 antigen; CD2 molecule; LFA2; LFA3 receptor; Lymphocyte function antigen 2; p50; Rosette receptor; Sheep erythrocyte receptor; Sheep red blood cell receptor; SRBC; T cell surface antigen CD2; T cell surface antigen T11/Leu 5; T11; CD2_HUMAN.  

研究领域 :  细胞生物  免疫学  细胞表面分子  糖蛋白  自然杀伤细胞  淋巴细胞  t-淋巴细胞  b-淋巴细胞  

抗体来源 :  Mouse

克隆类型 :  Monoclonal

克 隆 号 :  HIT11

交叉反应 :   Human,

产品应用 :  Flow-Cyt=20μl/Test  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  37kDa

细胞定位 :  细胞膜

性    状 :  Liquid

亚    型 :  IgG1

纯化方法 :  affinity purified by Protein G

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes.

Function:

CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Subunit:

Interacts with CD2AP. Interacts with PSTPIP1.

Subcellular Location:

Membrane; Single-pass type I membrane protein.

Similarity:

Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:

P06729

Gene ID:

914

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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