产品货号 :  mlR8473

英文名称 :  FBXL20

中文名称 :  FBXL20蛋白抗体

别    名 :  F box/LRR repeat protein 20; F box/LRR repeat protein 2 like; F box/LRR repeat protein 20; Fbl2; Fbl20; F box and leucine rich repeat protein 20; MGC15482; SCR; SCRAPPER; FXL20_HUMAN.  

研究领域 :  细胞生物  免疫学  神经生物学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,

产品应用 :  WB=1:500-2000  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  48kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human FBXL20:1-100/436

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Function:

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission.

Subunit:

Interacts with SKP1 and CUL1.

Subcellular Location:

Cytoplasmic.

Similarity:

Contains 1 F-box domain.

Contains 13 LRR (leucine-rich) repeats.

SWISS:

Q96IG2

Gene ID:

84961

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片