产品货号 :  mlR1250

英文名称 :  Gax

中文名称 :  生长终止特异性同源盒基因抗体

别    名 :  growth arrest-specific homeobox; Homeobox protein MOX-2; Mesenchyme homeobox 2; mesenchyme homeobox 2-like; Growth arrest-specific homeobox; GAX; growth arrest homeobox transcription factor GAX; mesenchyme homeobox 2; MEOX2_HUMAN.  

研究领域 :  肿瘤  心血管  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  33kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Gax:201-304/304

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimers disease.

Function:

Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle (By similarity).

Subunit:

Interacts with RNF10.

Subcellular Location:

Nucleus. Nucleus speckle.

Similarity:

Contains 1 homeobox DNA-binding domain.

SWISS:

P50222

Gene ID:

4223

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.