产品货号 :  mlR12897

英文名称 :  TAF172

中文名称 :  转录起始因子TFIID亚基170抗体

别    名 :  ATP dependent helicase BTAF1; ATP-dependent helicase BTAF1; B-TFIID transcription factor associated 170 kDa subunit; B-TFIID transcription factor associated, 170kDa (Mot1 homolog, S. cerevisiae); B-TFIID transcription factor-associated 170 kDa subunit; BTAF 1 RNA polymerase II; BTAF1; BTAF1 RNA polymerase II B TFIID transcription factor associated 170kDa; BTAF1_HUMAN; MOT 1; MOT1; MOT1 Yeast homolog of; TAF 172; TAF II 170; TAF(II)170; TAF-172; TAFII170; TATA binding protein associated factor 172; TATA-binding protein-associated factor 172; TBP associated factor 172; TBP-associated factor 172.  

研究领域 :  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  207kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human TAF172:181-280/1849

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]

Function:

Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner.

Subcellular Location:

Nucleus.

Similarity:

Belongs to the SNF2/RAD54 helicase family.

Contains 8 HEAT repeats.

Contains 1 helicase ATP-binding domain.

Contains 1 helicase C-terminal domain.

SWISS:

O14981

Gene ID:

9044

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.