产品货号 :  mlR0543

英文名称 :  Chromogranin B

中文名称 :  嗜铬粒素B抗体

别    名 :  Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B.  

研究领域 :  肿瘤  神经生物学  内分泌病  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  72kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human CGB:

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].

Function:

Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

Subcellular Location:

Secreted. Note=Neuroendocrine and endocrine secretory granules.

Tissue Specificity:

Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.

Post-translational modifications:

Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.

O-glycosylated.

Similarity:

Belongs to the chromogranin/secretogranin protein family.

SWISS:

P05060

Gene ID:

1114

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

嗜铬粒素B在肾上腺 垂体 胸腺 子宫 卵巢等神经内分泌组织表达该蛋白成分较多。