产品货号 :  mlR8175

英文名称 :  GTF2H1

中文名称 :  通用转录因子2H肽1抗体

别   名 :  Basic transcription factor 2 62 kDa subunit; Basic transcription factor 62 kDa subunit; BTF 2; BTF2 p62; General transcription factor IIH polypeptide 1; General transcription factor IIH subunit 1; gtf2h1; TF2H1; TF2H1_HUMAN; TFIIH basal transcription factor complex p62 subunit.  

研究领域 :  细胞生物  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  62kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human GTF2H1:201-300/548

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.

Function:

Component of the core-TFIIH basal transcription factorinvolved in nucleotide excision repair (NER) of DNA and, whencomplexed to CAK, in RNA transcription by RNA polymerase II.

Subunit:

One of the 6 subunits forming the core-TFIIH basaltranscription factor which associates with the CAK complex composedof CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basaltranscription factor. Interacts with PUF60.

Subcellular Location:

Nucleus.

Similarity:

Contains 2 BSD domains.

SWISS:

P32780

Gene ID:

2965

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片