产品货号 :  mlR19179

英文名称 :  MYOM3

中文名称 :  肌间蛋白3抗体

别    名 :  MYOM3; MYOM3_HUMAN; Myomesin family member 3; Myomesin-3; RP11-293P20.1.  

研究领域 :  肿瘤  细胞生物  免疫学  神经生物学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Horse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  162kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MYOM3:1001-1100/1437

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   MYOM3 is a 1,437 amino acid protein that contains five fibronectin type-III domains and four Ig-like C2-type (immunoglobulin-like) domains. Existing as three alternatively spliced isoforms, the gene that encodes myomesin-3 maps to human chromosome 1p36.11 and mouse chromosome 4 D3. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Subunit:

Homodimer.

Subcellular Location:

Cytoplasm, myofibril, sarcomere

Similarity:

Contains 5 fibronectin type-III domains.

Contains 4 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:

Q5VTT5

Gene ID:

127294

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.