产品货号 :  mlR2450

英文名称 :  CCL1 precursor

中文名称 :  嗜酸粒细胞趋化蛋白CCL1前体蛋白抗体

别    名 :  I-309; TCA3; C-C motif chemokine 1 precursor; chemokine (C-C motif) ligand 1; BF534335; Scya1; Chemokine CC Motif Ligand 1; inflammatory cytokine I-309; P500; SCYA1; SISe; small inducible cytokine A1; Ccl1; Small-inducible cytokine A1; T lymphocyte secreted protein I-309; CCL1_HUMAN.  

研究领域 :  细胞生物  免疫学  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Pig, Rabbit,

产品应用 :  ELISA=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  10kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human C-C motif chemokine 1 precursor:21-30/96

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq, Jul 2008].

Function:

Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.

Subunit:

Monomer.

Subcellular Location:

Secreted.

Similarity:

Belongs to the intercrine beta (chemokine CC) family.

SWISS:

P22362

Gene ID:

6346

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CCL1属于CC趋化因子家族，是由活化的T细胞分泌的糖蛋白。CCL1是一小分子的细胞因子C与细胞表面的趋化因子受体CCR8结合,对单核细胞，自然杀伤细胞，未成熟的B细胞和树突状细胞有细胞趋化作用.