产品货号 : mlR10773
英文名称 : CTR1
中文名称 : 铜离子转运蛋白1抗体
别 名 : Copper transport 1 homolog; Copper transporter 1; COPT1; COPT1_HUMAN; CTR1; hCTR1; High affinity copper uptake protein 1; SLC31A1; solute carrier family 31 (copper tansporters) member 1; Solute carrier family 31 member 1.
研究领域 : 神经生物学 通道蛋白 细胞膜受体
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 21kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human CTR1:51-150/190 <Cytoplasmic>
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
Function:
High-affinity, saturable copper transporter involved in dietary copper uptake.
Subunit:
Homotrimer.
Subcellular Location:
Cell membrane. Localizes to the apical membrane in intestinal epithelial cells.
Post-translational modifications:
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
Similarity:
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
SWISS:
O15431
Gene ID:
1317
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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