产品货号 : mlR19257
英文名称 : NKTR
中文名称 : 自然杀伤细胞亲环素相关蛋白抗体
别 名 : NK-TR protein Natural killer triggering receptor; Natural killer tumor recognition sequence; Natural-killer cells cyclophilin-related protein; NK-TR protein; NK-tumor recognition protein; Nktr; NKTR_HUMAN; p104.
研究领域 : 肿瘤 细胞生物 自然杀伤细胞
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 165kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human NKTR:321-420/1462
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008]
Function:
Component of a putative tumor-recognition complex. Involved in the function of NK cells.
Subunit:
Contains 1 PPIase cyclophilin-type domain.
Subcellular Location:
Membrane. Attached to the membrane via its N-terminus.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
SWISS:
P30414
Gene ID:
4820
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.