产品货号 :  mlR4492

英文名称 :  PKN beta

中文名称 :  蛋白激酶C相关激酶β抗体

别    名 :  PKN3; PKN3_HUMAN; PKNBETA; Protein kinase C related kinase 3; Protein kinase N3; Protein kinase PKN beta; Protein kinase PKN-beta; Protein-kinase C-related kinase 3; RP11-545E17.1; Serine/threonine protein kinase N3; Serine/threonine-protein kinase N3.  

研究领域 :  肿瘤  细胞生物  信号转导  激酶和磷酸酶  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  99kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PKN beta:791-889/889

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Contributes to invasiveness in malignant prostate cancer.

Subcellular Location:

Nucleus. Cytoplasm > perinuclear region. Nuclear and perinuclear Golgi region.

Tissue Specificity:

Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.

Post-translational modifications:

Autophosphorylated.

Similarity:

Belongs to the protein kinase superfamily.

AGC Ser/Thr protein kinase family.

PKC subfamily.

Contains 1 AGC-kinase C-terminal domain.

Contains 1 protein kinase domain.

Contains 3 REM (Hr1) repeats.

SWISS:

Q6P5Z2

Gene ID:

29941

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.