产品货号 :  mlR3525

英文名称 :  SIGLEC14

中文名称 :  唾液酸结合性免疫球蛋白样凝集素14抗体

别    名 :  Sialic acid binding Ig like lectin 14; Siglec 14; Siglec-14; SIG14_HUMAN.  

研究领域 :  肿瘤  细胞生物  免疫学  转录调节因子  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  42kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SIGLEC14:51-150/396 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   SIGLEC14 is a putative adhesion molecule. It may activate associated receptors.

Function:

Putative adhesion molecule. Sialic acid-binding pairedreceptor which may activate associated receptors.

Subunit:

Interacts with TYROBP.

Subcellular Location:

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:

Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Also detected in lung and testis.

Similarity:

Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:

Q08ET2

Gene ID:

100049587

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.