产品编号 : mlR9708
英文名称 : LCE1A
中文名称 : 晚期包膜蛋白1抗体
别 名 : Late cornified envelope 1A; Late cornified envelope protein 1A; Late envelope protein 1; LCE1A; LCE1A_HUMAN; LEP1.
研究领域 : 细胞生物 免疫学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 11kDa
细胞定位 : 细胞浆 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human LCE1A:21-100/110
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍background :
LCE1A belongs to the late cornified envelope (LCE) genecluster within the epidermal differentiation complex (EDC) onchromosome 1. The LCE cluster contains multiple conserved genesthat encode stratum corneum proteins, and these genes are expressedrelatively late during fetal assembly of the skin cornifiedenvelope (Jackson et al., 2005 [PubMed 15854049]). For furtherinformation on the LCE gene cluster, see GENE FAMILYbelow.[supplied by OMIM, Feb 2009].
Function:
Precursors of the cornified envelope of the stratum corneum.
Tissue Specificity:
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.
Similarity:
Belongs to the LCE family.
SWISS:
Q5T7P2
Gene ID:
353131
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.