产品货号 :  mlR18186

英文名称 :  LCE6A

中文名称 :  晚期角质化包膜蛋白抗体

别    名 :  C1orf44; Late cornified envelope 6A; Late cornified envelope protein 6A; LCE6A; LCE6A_HUMAN.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  9kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LCE6A:21-80/80

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   LCE6A is an 80 amino acid protein belonging to the LCE family. The LCE gene cluster within the epidermal differentiation complex on human chromosome 1 and mouse chromosome 3 contains multiple conserved genes encoding stratum-corneum proteins. Within the LCE cluster, genes form “groups” based on chromosomal position and protein homology. LCE6A is a precursor of the cornified envelope of the stratum corneum and belongs to the LCE cluster present on human chromosome 1q21. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, including Stickler syndrome, Parkinsons and Gaucher disease.

Function:

Precursors of the cornified envelope of the stratum corneum.

Similarity:

Belongs to the LCE family.

SWISS:

A0A183

Gene ID:

448835

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.