产品货号 :  mlR12733

英文名称 :  PLP2

中文名称 :  蛋白脂质蛋白2抗体

别    名 :  A4; A4 differentiation dependent protein; A4-LSB; A4LSB; differentiation dependent protein A4; Differentiation-dependent protein A4; Intestinal membrane A4 protein; MGC126187; PLP2; PLP2_HUMAN; proteolipid protein 2 (colonic epithelium enriched); Proteolipid protein 2.  

研究领域 :  细胞生物  信号转导  细胞周期蛋白  细胞分化  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Pig, Horse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  17kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PLP2:1-100/152

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]

Function:

May play a role in cell differentiation in the intestinal epithelium.

Subcellular Location:

Membrane.

Tissue Specificity:

Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.

Similarity:

Contains 1 MARVEL domain.

SWISS:

Q04941

Gene ID:

5355

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.