产品货号 :  mlR18696R

英文名称 :  Matriptase 3

中文名称 :  蛋白裂解酶3抗体

别    名 :  MTSP 3; TMPRSS7; Transmembrane serine proteinase 7.  

研究领域 :  细胞生物  信号转导  泛素  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Chimpanzee,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  94kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Matriptase 3:81-180/843 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a member of von Willebrand factor A domain-containing protein family. The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies. It may also be involved in wound healing in the dentin-pulp complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Function:

Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position

Subunit:

Forms a heterodimer with SERPINA5.

Subcellular Location:

Membrane; single-pass type II membrane protein

Tissue Specificity:

Expressed in brain, ovary, testis, salivary gland, trachea and lung.

Post-translational modifications:

N-glycosylated

Similarity:

Belongs to the peptidase S1 family.

Contains 2 CUB domains.

Contains 3 LDL-receptor class A domains.

Contains 1 peptidase S1 domain.

Contains 1 SEA domain.

SWISS:

Q7RTY8

Gene ID:

344805

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.