产品货号 :  mlR9510

英文名称 :  PAR3

中文名称 :  蛋白酶激活受体3抗体

别   名 :  Proteinase Activated Receptor 3; coagulation factor II (thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Thrombin receptor-like 2.  

研究领域 :  心血管  细胞生物  信号转导  G蛋白偶联受体  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  42kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PAR3:121-220/374 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Tissue specificity:

Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Function:

Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Subcellular Location:

Cell membrane.

Tissue Specificity:

Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Post-translational modifications:

A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Similarity:

Belongs to the G-protein coupled receptor 1 family.

SWISS:

O00254

Gene ID:

2151

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片