产品货号 :  mlR16852

英文名称 :  KAP8.1

中文名称 :  角蛋白相关蛋白KAP8.1抗体

别    名 :  High glycine-tyrosine keratin-associated protein 8.1; KAP8.1; Keratin-associated protein 8-1; KRA81_HUMAN; Krtap8-1; OTTHUMP00000063454.  

研究领域 :  细胞生物  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat, Pig, Cow, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  7kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human KAP8.1:12-50/63

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Subunit:

Interacts with hair keratins.

Tissue Specificity:

Is essentially restricted to only one vertical half of the hair forming compartment and in beard hairs is absent from the central medulla.

Similarity:

Belongs to the KRTAP type 8 family.

SWISS:

Q8IUC2

Gene ID:

337879

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.