产品货号 : mlR6359
英文名称 : Glutamine PRPP amidotransferase
中文名称 : 谷氨酰胺磷酸核糖基焦磷酸酰胺基转移酶
别 名 : Amidophosphoribosyltransferase [Precursor]; ATASE; Glutamine phosphoribosylpyrophosphate amidotransferase; Glutamine PRPP amidotransferase; GPAT; Phosphoribosyl pyrophosphate amidotransferase; PPAT; PRAT; PUR1_HUMAN.
研究领域 : 细胞生物 信号转导 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 56kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human Glutamine PRPP amidotransferase:351-430/517
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : Phosphoribosyl pyrophosphate amidotransferase (PPAT) is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. The genes for PPAT and PAICS/AIRC, (a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway), are located in close proximity on chromosome 4.
Subunit:
Homotetramer.
Tissue Specificity:
Ubiquitously expressed.
Similarity:
n the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Contains 1 glutamine amidotransferase type-2 domain.
SWISS:
Q06203
Gene ID:
5471
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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