产品货号 :  mlR1939

英文名称 :  ZNF474/ZFP106

中文名称 :  锌指蛋白474抗体

别    名 :  zinc finger protein; ZFP106; DKFZp451A239; FLJ34610; FLJ45841; SH3 domain binding protein 3; SH3BP3; Zfp 106; Zinc finger protein 106 homolog (mouse); Zinc finger protein 106 homolog; Zinc finger protein 474; ZNF474.  

研究领域 :  细胞生物  染色质和核信号  转录调节因子  锌指蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  207kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZNF474:701-800/1883

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   ZFP106 is a new candidate transcription factor. It contains 2 C2H2-type zinc fingers and 6 WD repeats. May play a role in modulating tissue specificity to insulin (isoform 3). Widely expressed, including lymphocytes.Isoform 3 is most abundant in insulin-sensitive tissues such as skeletal muscle, heart, fat, kidney and liver. Expression is regulated by insulin (isoform 3).

Subunit:

Interacts with HPV type 6 protein E6. Does not interact significantly with E6 proteins from HPV types 11, 16, or 18. Interacts, via the Pro-rich regions, with the EVH1 domains of ENAH, EVL and VASP. Interacts with the first LIM domain of TES.

Subcellular Location:

Nucleus, nucleolus.

Similarity:

Contains 2 C2H2-type zinc fingers.

Contains 6 WD repeats.

SWISS:

Q9H2Y7

Gene ID:

64397

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.