产品货号 :  mlR19428

英文名称 :  PRRG4

中文名称 :  跨膜γ羧基酸蛋白4抗体

别    名 :  9930111I18Rik; MGC117538; Proline-rich gamma-carboxyglutamic acid protein 4; Proline-rich Gla protein 4; PRRG 4; PRRG4; TMG4; TMG4_HUMAN; Transmembrane gamma-carboxyglutamic acid protein 4.  

研究领域 :  肿瘤  细胞生物  免疫学  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Rat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  20kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PRRG4:51-150/226 <Extracellular>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  PRRG4 (Proline Rich And Gla Domain 4) is a Protein Coding gene. Diseases associated with PRRG4 include wagr syndrome. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is PRRG1.

Function:

GenomeRNAi human phenotypes for PRRG4: Increased vaccinia virus (VACV) infection Mildly decreased CFP-tsO45G cell surface transport Decreased viability in esophageal squamous lineage Increased shRNA abundance (Z-score > 2) Decreased shRNA abundance (Z-score < -2)

Subcellular Location:

Membrane.

Tissue Specificity:

Expressed in lung, liver, kidney, pancreas and placenta.

Post-translational modifications:

Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.

Similarity:

Contains 1 Gla (gamma-carboxy-glutamate) domain.

SWISS:

Q9BZD6

Gene ID:

79056

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.