产品货号 : mlR23054
英文名称 : PCDHAC2
中文名称 : 原钙粘蛋白介导的PCDHαC2受体抗体
别 名 : PCDH alpha C2; PCDHAC 2; PCDHAC-2; Protocadherin alpha C2; Protocadherin alpha subfamily C 2; PCDC2_HUMAN.
研究领域 : 细胞生物 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Cow,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 105kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human PCDHAC2:201-300/1007 <Extracellular>
亚 型 : IgG
纯化方法 : ffinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : PCDHAC2 (Protocadherin alpha C2) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific neuronal connections in the brain. PCDHAC2 is one of fifteen tandemly arranged genes within the alpha cluster of protocadherin genes on 5q31.
Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Location:
Cell membrane. Single-pass type I membrane protein.
Similarity:
Contains 6 cadherin domains.
SWISS:
Q9Y5I4
Gene ID:
56134
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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