产品货号 :  mlR16899

英文名称 :  KCNK16

中文名称 :  钾离子通道蛋白16抗体

别    名 :  2P domain potassium channel Talk 1; pancreatic potassium channel Talk 1; potassium channel subfamily K member 16; TALK 1; KCNKG_HUMAN; TALK1; TWIK related alkaline pH activated K(+) channel 1.  

研究领域 :  肿瘤  细胞生物  免疫学  神经生物学  通道蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  34kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human KCNK16:231-309/309

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

The protein encoded by the KCNK16 gene belongs to a family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH and is expressed predominantly in the pancreas. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Function:

Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.

Subunit:

Homodimer (Potential).

Subcellular Location:

Membrane; Multi-pass membrane protein

Similarity:

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

SWISS:

Q96T55

Gene ID:

83795

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.