产品货号 :  mlR10577

英文名称 :  Defensin alpha 5

中文名称 :  防御素α5抗体

别    名 :  alpha 5; alpha 5 Defensin; DEF5; DEF5_HUMAN; DEF5_RAT; Defa; Defa29; DEFA5; Defcr29; Defcr5; Defensin 5; Defensin alpha-5; Defensin alpha 5 Paneth cell specific; Defensin alpha 5 preproprotein; Defensin; Enteric defensin; HD 5; HD5; HD5(20-94); HD5(63-94); MGC129728; RD 5.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Rat,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  4.1kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Defensin alpha 5:31-94/94

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

Function:

Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

Subcellular Location:

Secreted. Cytoplasmic vesicle, secretory vesicle. Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.

Tissue Specificity:

Paneth cells of the small intestine (at protein level).

Post-translational modifications:

Glycosylated.

Similarity:

Belongs to the alpha-defensin family.

SWISS:

Q01523

Gene ID:

1670

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.