Characteristics:
Source Chinese Hamster Ovary cell line
Description Recombinant human IL-23 is composed of P40 (Ile23-Ser328) and P19 (Arg23-Pro189) subunits ,which linked
by GS-linker
（GSGSSRGGSGSGGSGGGGSKL）
Accession # P29460(P40), AAG37232(P19)
Predicted molecular 55.0 kDa (IL-23 single chain); 36.5 kDa (p40) & 18.5 kDa (p19)
Mass
Specification:
Appearance White powder, Colorless clear liquid after reconstitution
Purity ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions,
visualized by Coomassie staining)
Endotoxin ≤10 EU/mg by the LAL method
Activity Measured by its ability to induce Interferon gamma secretion by human
natural killer lymphoma NK-92 cells. The ED50 for this effect is ＜0.5 μg/mL.
Formulation Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% mannitol
and 0.01% Tween 80, pH 7.4
Size 50 μg/vial, 1 mg/vial
Handling and Storage:
Reconstitution It is recommended to redissolve in sterile deionized water.
Shipping The product is shipped with blue ice.
Storage & Stability 36 months at -20°C to -80°C in lyophilized state
6 months at -20°C to -80°C under sterile conditions after reconstitution
7-10 days at 2°C to 8°C under sterile conditions after reconstitution
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Bioactivity:
